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How long does it take to get food allergens out of your system? How long does it take for a reaction to start after eating a food? Symptoms usually start as soon as a few minutes after eating a food and as long as two hours after. In some cases, after the first symptoms go away, a second wave of symptoms comes back one to four hours later (or sometimes even longer). Can allergies keep you up at night? If allergies are keeping you awake at night, you 're not alone. In one study, only 17% of patients with allergies rated their sleep as optimal. About half of all people in the study said allergies and nasal congestion woke them up at night and also made it hard to fall asleep.
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